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Alexander Fleming




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In he was elected the Rector of the University of Edinburgh for a term of three years. Antisepticswhich were used at the time to treat infected wounds, often worsened the injuries. Antiseptics worked well on the surface, but deep wounds tended to shelter anaerobic bacteria from the antiseptic agent, and antiseptics seemed to remove beneficial agents produced that protected the patients in these cases at least as well as they removed bacteria, and did nothing to remove the bacteria that were out of reach. Testing the nasal secretions from a patient with a heavy cold, he found that nasal mucus had an inhibitory effect on bacterial growth. Although he was able to obtain larger amounts of lysozyme from egg whites, the enzyme was only effective against small counts of harmless bacteria, and therefore had little therapeutic potential.

History of penicillin Miracle cure. One sometimes finds, what one is not looking for. When I woke up just after dawn on September 28,I certainly didn't plan to revolutionize all medicine by discovering the world's first antibiotic, or bacteria killer. But I suppose that was exactly what I did. He was already well-known from his earlier work, and had developed a reputation as a brilliant researcher, but his laboratory was often untidy. On 3 SeptemberFleming returned to his laboratory having spent August on holiday with his family. Before leaving, he had stacked all his cultures of staphylococci on a bench in a corner of his laboratory.

On returning, Fleming noticed Hvoedan one culture was contaminated with a fungus, and that the colonies of staphylococci immediately surrounding the fungus had been destroyed, Hvoradn other Hovrdan colonies farther away were sn, famously remarking "That's funny". He identified the mould as being from the genus Penicilliumand, after some months of calling it "mould juice", named the farr it released penicillin on 7 March He investigated its positive anti-bacterial effect on many organisms, and noticed that it affected bacteria such as staphylococci and many other Gram-positive pathogens that cause scarlet feverpneumoniameningitis and diphtheriabut not typhoid fever or paratyphoid fever l, which are caused Hvordann Gram-negative bacteria, for which he was seeking a cure at the time.

It also affected Neisseria gonorrhoeaewhich causes gonorrhoeaalthough this bacterium is Gram-negative. Fleming published his discovery inin the British Journal of Experimental Pathology, [16] but little attention was paid to his article. Fleming continued his investigations, but found that cultivating Penicillium was quite difficult, and that after having grown the mould, it was even more difficult to isolate the antibiotic agent. Fleming's impression was that because of the problem of producing it in quantity, and because its action appeared to be rather slow, penicillin would not be important in treating infection. Fleming also became convinced that penicillin would not last long enough in the human body in vivo to kill bacteria effectively.

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Sod k en far jeg herlev Hvordan reste

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